Screening and suicide risk factors in major depression of adults

1. Would screening improve the results in major depression?
2. Are there suicide risk factors in patients with major depression?

Pharmacological treatment of depression

3. Is there any effective and safe drug for the treatment of mild, moderate or severe major depression?
4. Is any drug better than another for the treatment of major depression? What is the time-course for assessing the efficacy of a drug?
5. How long pharmacological treatment should be maintained after remission of depressive symptoms?
6. What pharmacological strategies are indicated for resistant depression?

Psychotherapy

8. Is any type of psychotherapy effective for patients with major depression?

Other treatments

9. Is electroconvulsive therapy effective for the treatment of major depression?
10. Is guided self-help effective for any sub-group of patients?
11. Are support groups effective for patients with major depression?
12. Is physical exercise effective for patients with major depression?
13. Is acupuncture effective for patients with major depression?
14. Is treatment with St John’s Wort effective?

Quality indicators

15. What are the indicators that allow monitoring quality in the management of depression?